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Huntington's disease is an inherited disease that causes certain nerve cells in the brain to waste away. It is a progressive and degenerative disease. A person could experience mental deterioration, uncontrolled movements and emotional disturbances as a result of this disease.
Usually, the signs and symptoms of Huntington disease develop in middle age. Children could develop Huntington's disease only in some rare cases. Younger people with this disease usually have a more severe case and their symptoms could also progress more quickly.
Even though treatments can't prevent the physical and mental decline that is associated with the condition, medications could help manage the signs and symptoms of this disease.
Prepared by: Scientific Section
The signs and symptoms of this disease could significantly vary from one person to another. This disease develops slowly and the degree of nerve cell loss determines the severity of signs and symptoms. Death occurs about 10 to 30 years after signs and symptoms first appear. In younger people, the disease may progress quicker.
A single abnormal gene causes Huntington's disease, which is an inherited condition. Because only one copy of the defective gene, which could be inherited from either parent, is necessary to produce the disease, Huntington's disease is usually referred to as autosomal dominant disorder. The chance of an offspring getting the disease is 50% in case one of the parents has the single faulty gene. Most parents don't know that they carry the gene until they've already had children and possibly passed on the trait, because the signs and symptoms appear first in middle age.
After the onset of Huntington's disease, the signs and symptoms continue to death. Over time, vital functions such as swallowing, eating, walking and speaking degenerate, however, these signs and symptoms vary from one person to another. One of the common complications in Huntington's disease is depression, and some people could even be at risk of suicide. A fall, an infection like pneumonia or other complications usually cause death.
There is no available treatment that could stop or reverse Huntington's disease. Eventually, Huntington's disease will cause physical and mental disability despite the fact that some approaches could control the signs and symptoms of the disease. Long-term nursing home care could be necessary as the disease progresses.
Dr. Talal Sabouni
Dr . Dirar Abboud
Dr. Samer Al-Jneidy
Dr. Hani Najjar
Dr. Faisal Dibsi
Yaser Habrawi , F.R.C.S.Ed
Dr. Tahsin Martini
Samir Moussa M.D.