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Indications:

Metamizol can be used for many different types of pain, including pain from different origins and various levels of intensity. Some examples include toothaches, headaches, mild to moderate internal pain, arthralgia and neuralgia, or fever. It can also be given when other forms of treatment don’t work effectively. It is also effective for treating acute or severe pain after surgeries, as well.

Contraindications:

Active gastroduodenal ulcer, liver failure, hepatitis, nephritis, blood dyscrasias, cardiac failure, oliguria. Do not be administered for prolonged periods. Metamizole magnesium (Magnopyrol) has not administered in case of allergy to pyrazolone (eg, hypersensitivity to drugs with Metamizole magnesium , isopirina, propyphenazone, phenazone or phenylbutazone), and certain metabolic disorders (hepatic porphyria, congenital deficiency of glucose-6-phosphate dehydrogenase), patients with hypersensitivity to analgesics (pain relievers asthma) infants during the first three months and less than 5 kg of weight, patients with blood pressure below 100 mm Hg or movement unstable hematopoiesis and injured patients.

Adverse reactions:

May be nausea, vomiting, diarrhea or constipation, urticaria, hypersensitivity to the drug. Rarely granulocytopenia, epigastric pain, stomatitis. Regardless of the dose, Metamizole magnesium (Magnopyrol) can occasionally determine hypersensitivity, externalized, such as rash, leukopenia and rarely agranulocytosis, as well as fragments of impact or shock. Presented unfamiliar or unpleasant sensations impaired skin and mucous membranes, will need to stop and seek medical preparations. If it had been observed previously and phenomena of intolerance to other analgesics or anti-flu preparations, consult your doctor before applying Metamizole magnesium (Magnopyrol). After intravenous injection, there may be dizziness, feeling of oppression and demonstrations by the CNS, without allergic genesis. After intravenous injection, there may be dizziness, feeling of oppression and demonstrations by the CNS, without allergic genesis.These side effects are largely avoided by slow injection (1 to 1.5 ml per minute). Rarely, injection Metamizole magnesium (Magnopyrol), depending on the dose may lead to hypotension, without hypersensitivity reactions.

Interactions:

In the simultaneous treatment with cyclosporin may decrease the level of fines, so control is required. We recommend avoiding alcoholic beverages while being received Metamizole magnesium (Magnopyrol) because it can increase the effect of these. With the threat of severe hypothermia, Metamizole magnesium (Magnopyrol) should not be administered with chlorpromazine. Since the magnesium content of Metamizole magnesium (Magnopyrol), oral application may decrease the absorption of iron and tetracyclines. Simultaneous administration of amantadine, quinidine, and tricyclic antidepressants can cause a stronger anticholinergic action.

Warnings:

Do not take during pregnancy or breastfeeding. They are not teratogenic or carcinogenic effects observed after administration of high doses in rats and which, for long periods. Anyway, Metamizole magnesium should not be used during pregnancy since there have been no human studies to evaluate their teratogenic potential.

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Consultants Corner

Yaser Habrawi , F.R.C.S.Ed

Yaser Habrawi , F.R.C.S.Ed Consultant Ophthalmologist

Dr . Dirar Abboud

Dr . Dirar Abboud Hepatologist – Gastroenterologist

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Dr. Samer Al-Jneidy Pediatrician

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