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Ciclokapron

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Indications:

Prevention of bleeding after surgery or trauma: Tooth extraction in patients with hemophilia Cervical conization Tonsillectomy and adenoidectomy Prostatic surgery Ocular trauma Oral surgery in patients taking anti-coagulants Prevention of rebleeding of subarachnoid hemorrhage. Treatment of primary or intrauterine device (IUD) - induced menorrhagia. Treatment of gastric and intestinal hemorrhage. Treatment of recurrent epistaxis. Prevention of spontaneous or post-operative corneal edema. Treatment of hereditary and non-hereditary angioedema. Prevention of bleeding in acute promyelocytic leukemia. Prevention of bleeding after bypass surgery.

Contraindications:

COUNTRA INDICATIONS: - Previous history of venous thromboembolic events (deep vein thrombosis, pulmonary embolism); - Previous history of arterial thromboembolic events (angina, myocardial infarction, stroke); - States fibrinolytic reaction to a consumptive coagulopathy; - Severe renal impairment (risk of accumulation); - Previous history of seizures. NOT RECOMMENDED: Breastfeeding: tranexamic acid is excreted in breast milk. Therefore, breastfeeding is recommended during the treatment period.

Adverse reactions:

Very rare side effects have been reported: - Gastrointestinal Disorders: digestive disorders such as nausea, vomiting and diarrhea. - Cardiovascular: . discomfort with hypotension with or without loss of consciousness (usually following a rapid intravenous injection, rarely after oral administration). . rare cases of thromboembolic events may occur in any territory. - Central nervous system and psychiatric manifestations: seizures, especially if risk factors or a history of seizures and in case of misuse (see cons-indications). - Allergic reactions: hypersensitivity reactions including anaphylactic reactions (urticaria, angioedema, anaphylactic shock) and various rashes.

Interactions:

Tell your doctor of all nonprescription or prescription medication you may use, especially of: aspirin/NSAIDs (e.g., ibuprofen), anticoagulants ("blood thinners" such as warfarin or heparin), aminocaproic acid, factor IX complex, anti-inhibitor coagulant concentrates, drugs that can cause blood clots (e.g., estrogens or birth control pills). Many nonprescription products contain aspirin/NSAIDs. Check labels carefully and consult your pharmacist. Do not start or stop any medicine without doctor or pharmacist approval.

Warnings:

Before using this drug, tell your doctor your medical history, including: any allergies, history of blood clots or bleeding, eye problems (retina/color vision), kidney disease, head injury (subarachnoid hemorrhage). Tell your doctor if you are pregnant before using this drug. This drug is excreted into human milk. Consult your doctor before breast-feeding.

Form:

SOLUTION FOR INJECTION

Dosage and Administration

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Consultants Corner

Dr. Talal Sabouni

Dr. Talal Sabouni UROLOGY AND KIDNEY TRANSPLANT

Dr. Samer Al-Jneidy

Dr. Samer Al-Jneidy Pediatrician

Dr. Tahsin Martini

Dr. Tahsin Martini Degree status: M.D. in Ophthalmology

Dr. Hani Najjar

Dr. Hani Najjar Pediatrics, Neurology

Dr. Faisal Dibsi

Dr. Faisal Dibsi Specialist of Otolaryngology - Head and Neck Surgery

Yaser Habrawi , F.R.C.S.Ed

Yaser Habrawi , F.R.C.S.Ed Consultant Ophthalmologist

Samir Moussa M.D.

Samir Moussa M.D. ENT Specialist

Dr . Dirar Abboud

Dr . Dirar Abboud Hepatologist – Gastroenterologist

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