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Luai Al Bakour
El Temamy Pharmacy
Akoni Hijyen Teknolojileri Sanayi ve Dış Ticaret LTD. ŞTİ
Britton Chance Center for Biomedical Photonics
Arabian Trade Center - ATC
Medical Facility (32206):
Legality International. (Pvt.) Ltd.
Venustat® Cap (120 Mg)
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orlistat is an anti-obesity agent. orlistat is used to help obese people lose weight and keep this weight off. It does not suppress your appetite or act on the brain. It works in the digestive system, where it blocks about one-third of the fat in the food you eat from being digested. Since fat contains more calories than other components in foods, cutting the fat that is digested by your body is an effective way to limit daily calories and lose weight. It is a potent, specific and long-acting inhibitor of gastrointestinal lipases. The inactivated enzyme is thus unavailable to hydrolyse dietary fat, and this allows about 30% of the fat eaten in the meal to pass through the gut undigested. Your body therefore, cannot use this dietary fat as a source of energy and convert it to fat tissue. This will help you reduce your weight. orlistat is indicated in the treatment of obesity in conjunction with a mildly hypocaloric diet.
You should not breast-feed while on orlistat , as it is not known whether orlistat passes into human milk. Orlistat is not recommended for use during pregnancy.
The majority of unwanted effects related to the use of Xenical result from its local action in your digestive system. These commonly include: urgent or increased need to open the bowels, flatulence (wind) with discharge, oily discharge and oily or fatty stools. The possibility of this happening may increase if Xenical is taken with a diet high in fat. In addition your daily intake of fat should be distributed evenly over three main meals because if orlistat is taken with a meal very high in fat, the possibility of gastrointestinal effects may increase. The more fat you eat, the more fat in your stools, and the more you will experience these dietary events. The frequency and onset of these dietary events varies from one person to another and depends on how much fat is consumed. They usually occur more frequently in the beginning of your program, and will gradually disappear as you develop new eating habits. Most importantly, you can control these dietary events when you control your fat intake. It is not orlistat alone, but the excess fat that you eat while taking XENICAL that causes these events. Try not to exceed your daily fat allowance as calculated by your doctor or dietician. Rare cases of allergic reactions have occurred with Xenical. The main symptoms are itching, rash, wheals (slightly elevated, itchy skin patches that are paler or redder than surrounding skin), difficulty in breathing, nausea, vomiting and feeling unwell. Very rarely increases in liver enzyme levels have been reported. If you are concerned about these or notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.
Weight loss may also affect the dose of medication taken for other conditions (e.g. high cholesterol or diabetes). Be sure to discuss these and other drugs you may be taking with your doctor. Losing weight may mean you need adjustments to the dose of these medications. orlistat may modify the activity of anticoagulant drugs (e.g. warfarin). Your doctor may need to monitor your blood coagulation. Xenical may modify the activity of cyclosporin. Your doctor may need to monitor your blood levels more frequently than usual. orlistat reduces the absorption of supplements of some fat soluble nutrients, particularly beta-carotene and vitamin E. You should therefore follow your doctors advice in taking a well balanced diet rich in fruit and vegetables. Your doctor may suggest you take a multivitamin supplement.
Do not take orlistat if: you are hypersensitive (allergic) to orlistat or any of the other ingredients of Xenical. you have chronic malabsorption syndrome (insufficient absorption of nutrients from alimentary tract), you have cholestasis (liver disorder).
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Yaser Habrawi , F.R.C.S.Ed
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