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Pantosec D

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Indications:

Short-Term Treatment of Erosive Esophagitis Associated With Gastroesophageal Reflux Disease (GERD) Maintenance of Healing of Erosive Esophagitis Pathologica Hypersecretory Conditions Including Zollinger-Ellison Syndrome

Contraindications:

PANTOPRAZOLE is contraindicated in patients with known hypersensitivity to any component of the formulation

Adverse reactions:

Headache 6, Diarrhea 4, Flatulence 2, Abdominal pain 1, Rash < 1, Eructation 1, Hyperglycemia 1.

Interactions:

Theophylline, cisapride, antipyrine, caffeine, carbamazepine, diazepam, diclofenac, naproxen, piroxicam, digoxin, ethanol, glyburide, levonorgestrel/ethinyl estradiol, metoprolol, nifedipine, phenytoin, warfarin , midazolam, clarithromycin, metronidazole, or amoxicillin, ketoconazole, ampicillin esters, and iron salts.

Warnings:

Nursing Mothers: a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother. Pediatric Use: Safety and effectiveness in pediatric patients have not been established. Renal Impairment: No dosage adjustment is necessary in patients with renal impairment or in patients undergoing hemodialysis. Hepatic Impairment: No dosage adjustment is needed in patients with mild to severe hepatic impairment. Doses higher than 40 mg/day have not been studied in hepatically-impaired patients. OVERDOSAGE: There have also been spontaneous reports of patients taking similar amounts of pantoprazole (400 mg and 600 mg) with no adverse effects. Pantoprazole is not removed by hemodialysis. In case of overdosage, treatment should be symptomatic and supportive.

Form:

TABLET

Dosage and Administration

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