Indications:

Influenza States Common cold Acute and chronic catarrhal States Rhinosinusitis Cooling Diseases Allergic rhinitis catarrhal

Contraindications:

Hypersensitivity to any of the active ingredients. Severe hypertension. Anemia. Patients receiving MAOI type drug. Patients with narrow angle glaucoma. Prostatic hypertrophy. Stenosing peptic ulcer. Pylorus-duodenal obstruction. Bladder neck obstruction. Premature newborns.

Adverse reactions:

Cardiovascular: arrhythmia or hypertension with different degrees of severity and frequency. Respiratory: occasionally, tachypnea. Gastrointestinal: occasionally nausea, vomiting, dry mouth , diarrhea and abdominal pain. CNS: occasionally tiredness, somnolence, dizziness and headaches, blurred vision (accommodation disorders). Genitourinary: rarely, slight micturition disorders (urinary retention). General: rarely blood dyscrasia, urticaria.

Interactions:

Pseudoephedrine: Pseudoephedrine reduces antihypertensive effect when coadministered with an antihypertensive agent and increases the effect of CNS stimulants. Thyroid hormones increase the effects of pseudoephedrine. Coadministration of pseudoephedrine with digitalis or MAOIs increases the risk of cardiac arrhythmias. Chlorpheniramine: Chlorpheniramine potentiates depressant effects on the Central Nervous System when coadministered with CNS depressants (benzodizepines, barbiturates and/or alcohol). With central anticholinergics, potentiation of atropinic effects occur. Paracetamol: Paracetamol increases the effect of oral anticoagulants. Coadministration of paracetamol with oral contraceptives reduces the analgesic effect. Barbiturates and probenecid may increase paracetamol toxicity . Metoclopramide increases the absorption and effect of paracetamol.

Warnings:

Prolonged treatment with the product or possible overdose can cause serious liver problems. Pregnancy and lactation: Not recommended for administration of the product during pregnancy, nor during lactation, given that data are lacking to ensure the safety of its components in such states.

Form:

QURA PLUS Film-coated tablets: packages containing