Indications:

Osteoarthritis,Rheumatoid arthritis,Acute pain.

Contraindications:

Peptic ulcer, hypersensitivity to etodolac/NSAIDs. Childn; pregnancy (3rd trimester) and lactation.

Adverse reactions:

GI disturbances; CNS effects; hypersensitivity reactions. Rash, pruritus; neuromuscular and skeletal weaknesses; blurred vision. Potentially Fatal: Acute renal failure; blood disorder; nephrotoxicity; angioedema, arrhythmia, bone marrow suppression, CHF, dyspnoea, erythema multiforme, exfoliative dermatitis, hepatitis, hypertension, peripheral neuropathy, Stevens-Johnson syndrome, syncope, tachycardia, toxic amblyopia, toxic epidermal necrolysis, urticaria.

Interactions:

Increased effect of warfarin, lithium, methotrexate, digoxin, cyclosporin, aspirin. Effect may be reduced with aspirin. Reduced effect of some diuretics and β-blockers. Alcohol enhances gastric mucosal irritation. Food Interaction Peak serum levels and GI distress decreased when taken with food. Cat''s claw, dong quai, evening primrose, feverfew, ginkgo, red clover, horse chestnut, green tea and ginseng enhance the antiplatelet effect. Lab Interference False-positive for urinary bilirubin and ketones. Increased bleeding time.

Warnings:

CHF, dehydration, impaired renal, hepatic function, history of GI disease. Elderly, patients receiving anticoagulant. Pregnancy: Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

Form:

Film Coated Tablets