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Biprin

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Indications:

* Sideroblastic anaemia * Treatment and prophylaxis of vitamin B6 deficiency states

Contraindications:

Adverse reactions:

CNS Neuropathy; unstable gait; drowsiness; somnolence. EENT Perioral numbness. Miscellaneous Numbness of feet; decreased sensation to touch, temperature or vibration; paresthesia; low serum folic acid levels; burning/stinging at IM injection site; photoallergic reaction; ataxia.

Interactions:

Cycloserine, isoniazid, hydralazine, oral contraceptives, penicillamine Increased need for pyridoxine. Levodopa Decreased effect of levodopa. (Interaction does not occur with levodopa/carbidopa in combination with pyridoxine.) Phenytoin Phenytoin serum levels may be decreased. Incompatibility Incompatible with alkaline solutions, iron salts and oxidizing agents (parenteral). Laboratory Test Interactions May result in false-positive urobilinogen in the spot test using Ehrlich reagent.

Warnings:

Pregnancy Category A . ( Category C in doses that exceed the RDA.) Lactation Excreted in breast milk; may inhibit lactation. Children Safety and efficacy not established in doses exceeding nutritional requirements.

Form:

SOLUTION FOR INJECTION

Dosage and Administration

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