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Indications:

For treatment of primary dysmenorrhe. For relief of mild to moderate pain. For relief of the signs and symptoms of osteoarthritis. For relief of the signs and symptoms of rheumatoid arthritis.

Contraindications:

In patients with known hypersensitivity to diclofenac. In patients who have experienced asthma, urticaria, or allergic- type reactions after taking aspirin or other NSAIDs.

Adverse reactions:

Gastrointestinal experiences including: abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea, vomiting. Anemia, dizziness, edema, elevated liver enzymes and headache.

Interactions:

Not to be given IV to patients who are receiving other NSAIDs or anticoagulants including low dose heparin. Renal function may be worsened when used with ciclosporin or triamterene. Altered absorption when given with sucralfate, colestyramine or colestipol. Ophthalmic application of diclofenac may reduce the efficacy of ophthalmic acetylcholine and carbachol. Increased risk of GI ulceration and bleeding when used with corticosteroids, aspirin or anticoagulants. Potentially Fatal: Increases blood levels of digoxin, lithium and methotrexate. Potentiate potassium-sparing diuretics. Food Interaction Slow absorption of enteric-coated tab when given with food.

Warnings:

Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids.

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