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Dibasona

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Indications:

Conditions amenable to systemic glucocorticoid therapy, esp for acute situations.

Contraindications:

Systemic therapy Peptic ulcers; systemic fungal infection; varicella & herpes genitalia infection; glaucoma. Local therapy Septic arthritis from gonorrhea or TB, instability of the joints. Hypersensitivity to glucocorticoids.

Adverse reactions:

GI disorders; skin atrophy, acne; psychic disturbances, convulsions; glaucoma, increased intraocular pressure, posterior subcapsular cataracts; fluid & electrolyte disturbances; Cushing-like syndrome, premature epiphyseal closure, menstrual irregularities; myopathy, abdominal distension, osteoporosis, aseptic necrosis of femoral & humeral heads; following IV inj of large doses, transient burning or tingling sensation.

Interactions:

Hypokalemia w/ diuretics &/or cardiac glycosides. Reduced effectiveness w/ rifampicin, ephedrine, barbiturates, phenytoin & primidone. Alters effects of oral anticoagulant. NSAIDs may increase severity of GI ulceration. Antidiabetic agents & active vaccines.

Warnings:

Latent or overt cardiac failure, renal dysfunction, HTN, epilepsy, migraine; history of psychotic illness; latent TB; incomplete statural growth; live vaccines. Pregnancy, lactation; osteoporosis. Pregnancy: Hypokalemia w/ diuretics &/or cardiac glycosides. Reduced effectiveness w/ rifampicin, ephedrine, barbiturates, phenytoin & primidone. Alters effects of oral anticoagulant. NSAIDs may increase severity of GI ulceration. Antidiabetic agents & active vaccines. Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

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Consultants Corner

Yaser Habrawi , F.R.C.S.Ed

Yaser Habrawi , F.R.C.S.Ed Consultant Ophthalmologist

Dr . Dirar Abboud

Dr . Dirar Abboud Hepatologist – Gastroenterologist

Samir Moussa M.D.

Samir Moussa M.D. ENT Specialist

Dr. Talal Sabouni

Dr. Talal Sabouni UROLOGY AND KIDNEY TRANSPLANT

Dr. Samer Al-Jneidy

Dr. Samer Al-Jneidy Pediatrician

Dr. Faisal Dibsi

Dr. Faisal Dibsi Specialist of Otolaryngology - Head and Neck Surgery

Dr. Tahsin Martini

Dr. Tahsin Martini Degree status: M.D. in Ophthalmology

Dr. Hani Najjar

Dr. Hani Najjar Pediatrics, Neurology

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