Home
My Account
About Us
Forum
Contact us
الواجهة العربية
epharmaweb.com
Medical News Medical News
Aricles Articles
Events Events
Guidelines Guidelines
Videos Library Videos Library
Diseases Diseases
Follow us : facebook twitter Digg Linkedin Boxiz
Newsletter

Please select the categories you are intersted in:
News Articles Guidelines Events Videos Journals' abstracts

Latest Subscribers
Advanced Search »



Number of Coronary Heart Disease Risk Factors and Mortality in Patients With First Myocardial Infarction



Number of Coronary Heart Disease Risk Factors and Mortality in Patients With First Myocardial Infarction

John G. Canto, MD, MSPH; Catarina I. Kiefe, MD, PhD; William J. Rogers, MD; Eric D. Peterson, MD, MPH; Paul D. Frederick, MPH, MBA; William J. French, MD; C. Michael Gibson, MD; Charles V. Pollack, Jr, MD, MA; Joseph P. Ornato, MD; Robert J. Zalenski, MD; Jan Penney, RN, MSN; Alan J. Tiefenbrunn, MD; Philip Greenland, MD for the NRMI Investigators

The Journal of the American Medical Association,
306:19, November 16, 2011

Number of Coronary Heart Disease Risk Factors and Mortality in Patients With First Myocardial Infarction

Context
Few studies have examined the association between the number of coronary heart disease risk factors and outcomes of acute myocardial infarction in community practice.


Objective
To determine the association between the number of coronary heart disease risk factors in patients with first myocardial infarction and hospital mortality.


Design
Observational study from the National Registry of Myocardial Infarction, 1994-2006.


Patients
We examined the presence and absence of 5 major traditional coronary heart disease risk factors (hypertension, smoking, dyslipidemia, diabetes, and family history of coronary heart disease) and hospital mortality among 542 008 patients with first myocardial infarction and without prior cardiovascular disease.


Main Outcome
Measure All-cause in-hospital mortality.


Results
A majority (85.6%) of patients who presented with initial myocardial infarction had at least 1 of the 5 coronary heart disease risk factors, and 14.4% had none of the 5 risk factors. Age varied inversely with the number of coronary heart disease risk factors, from a mean age of 71.5 years with 0 risk factors to 56.7 years with 5 risk factors (P for trend < .001). The total number of in-hospital deaths for all causes was 50 788. Unadjusted in-hospital mortality rates were 14.9%, 10.9%, 7.9%, 5.3%, 4.2%, and 3.6% for patients with 0, 1, 2, 3, 4, and 5 risk factors, respectively. After adjusting for age and other clinical factors, there was an inverse association between the number of coronary heart disease risk factors and hospital mortality adjusted odds ratio (1.54; 95% CI, 1.23-1.94) among individuals with 0 vs 5 risk factors. This association was consistent among several age strata and important patient subgroups.


Conclusion
Among patients with incident acute myocardial infarction without prior cardiovascular disease, in-hospital mortality was inversely related to the number of coronary heart disease risk factors.







اضغط هنا للقراءة باللغة العربية

Prepared by: Dr. Houssam Al-Nahhas






Forgot your password


sign up

Consultants Corner

Dr. Faisal Dibsi

Dr. Faisal Dibsi Specialist of Otolaryngology - Head and Neck Surgery

Dr . Dirar Abboud

Dr . Dirar Abboud Hepatologist – Gastroenterologist

Dr. Samer Al-Jneidy

Dr. Samer Al-Jneidy Pediatrician

Yaser Habrawi , F.R.C.S.Ed

Yaser Habrawi , F.R.C.S.Ed Consultant Ophthalmologist

Dr. Talal Sabouni

Dr. Talal Sabouni UROLOGY AND KIDNEY TRANSPLANT

Dr. Hani Najjar

Dr. Hani Najjar Pediatrics, Neurology

Samir Moussa M.D.

Samir Moussa M.D. ENT Specialist

Dr. Tahsin Martini

Dr. Tahsin Martini Degree status: M.D. in Ophthalmology
Poll

Which of the following you are mostly interested in?

Cancer Research
Mental Health
Heart Disease & Diabetes
Sexual Health
Obesity and Healthy Diets
Mother & Child Health

Disclaimer : This site does not endorse or recommend any medical treatment, pharmaceuticals or brand names. More Details