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this medicine is indicated for the relief of severe skeletal muscle spasm and pain associated with such medical and orthopaedic problems as: sprains and strains, myalgias, torticollis, tension headaches, traumatic muscle injuries, low back pain, fibrositis, cervical root and disc syndromes.


this medicine is contra-indicated in patients sensitive to either component.

Adverse reactions:

Occasional patients may develop gastrointestinal disturbances. It is possible, in rare instances, that chlorzoxazone may have been associated withgastrointestinal bleeding. Dizziness, nausea, lightheadedness, malaise, or overstimulation may be noted by an occasional patient. Drowsiness can occur with the use of this medicine and may be additive to drowsiness from the concomitant use of alcohol or other central nervous system depressants. Rarely, petechiae or ecchymoses may develop during treatment. Sensitivity reactions resulting in reversible skin rash or blood disorders may occur, but these are rare. Angioneurotic oedema and anaphylactic reactions are extremely rare. Rarely, a patient may note discolouration of the urine resulting from a phenolic metabolite of chlorzoxazone. This finding is of no known clinical significance. Infrequently, cases have been reported in which the administration of chlorzoxazone or chlorzoxazone containing products was suspected of causing liver damage. Several of these were subsequently determined to the due to underlying diseases rather than to chlorzoxazone (i.e. carcinoma of the head of the pancreas, carcinoma with hepatic metastases, cholelithiasis). The remaining cases had a clinical picture consistent with viral hepatitis or a medicine induced hepatitis. In all of the latter cases the medicine was stopped and the patients recovered. It is not possible to state that the hepatitis in these patients was or was not medicine-induced.



this medicine should be used with caution in patients with known allergies or with a history of allergic reactions to medicines. If a sensitivity reaction occurs such as urticaria, redness, or itching of the skin, the medicine should be stopped. If any signs or symptoms suggestive of liver dysfunction are observed the medicine should be discontinued. Patients suffering from liver or kidney disease should take this medicine under medical supervision. Do not use continuously for longer than ten days without consulting your doctor. Consult your doctor if no relief is obtained with the recommended dosage. *WARNINGS: this medicine is not recommended during pregnancy or lactation since safety in pregnant women or nursing mothers has not been established. Dosages in excess of those recommended may cause severe liver damage.



Dosage and Administration

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