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Ketazolam is used to treat symptoms of anxiety disorders (anxiety, agitation, restlessness, sleep disturbances, states of tension). Benzodiazepines are indicated only when the disorder is severe, disabling or submit the subject to severe discomfort.


Like other benzodiazepines, the product should not be used in case of myasthenia gravis, severe respiratory insufficiency, severe hepatic failure, sleep apnea syndrome, hypersensitivity to an individual found ketazolam or other benzodiazepines. The ketazolam is also contraindicated in the presence of acute angle glaucoma and in acute in acute poisoning by alcohol, analgesics, hypnotics, neuroleptics, antidepressants, lithium.

Adverse reactions:

Drowsiness, blunting of emotions, impaired alertness, confusion, fatigue, headache, dizziness, muscle weakness, ataxia, double vision. These phenomena occur predominantly at the beginning of therapy and usually disappear with subsequent doses.


Concomitant intake with alcohol should be avoided. The sedative effect may be increased when the drug is taken together with alcohol. This affects the ability to drive or operate machinery. Association with CNS depressants: the central depressive effect may be increased in cases of concomitant use with antipsychotics (neuroleptics), hypnotics, anxiolytics / sedatives, antidepressants, narcotic analgesics, antiepileptics, anesthetics, sedatives and antihistamines. Compounds that inhibit certain liver enzymes (especially cytochrome P450) may enhance the activity of benzodiazepines. may potentiate the action of muscle relaxants.


Tolerance Some loss of efficacy to the hypnotic effects of benzodiazepines may develop after repeated use for several weeks. Dependence The use of benzodiazepines can lead to the development of physical and psychic dependence with these drugs. The risk of dependence increases with dose and duration of treatment, it is higher in patients with a history of drug or alcohol abuse. Rebound insomnia and anxiety: the interruption of treatment may present a transient syndrome where the symptoms that led to treatment with benzodiazepines occur in aggravated form. May be accompanied by other reactions including mood changes, anxiety, restlessness or insomnia.



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