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Toplexil

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Indications:

This drug contains an antihistamine, oxomemazine, and guaifenesin. It is intended to soothe dry coughs and irritative coughs in adults and children over 1 year of age, in particular when they occur in the evening or at night.

Contraindications:

known allergy to its constituents, and to antihistamines in particular, - history of agranulocytosis ( severe fall in white blood cells), - difficulty urinating of prostatic or other origin, - certain types of glaucoma (increased pressure inside the eye). This drug SHOULD GENERALLY NOT BE USED, unless otherwise advised by your Physician. - during the first three months of pregnancy, nor in lactating mothers. - in combination with sultopride.

Adverse reactions:

Allergic reactions: a type of skin rash (erythema, eczema, purpura, urticaria); oedema (urticaria with sudden swelling of the face and neck which may cause difficulty breathing); anaphylactic shock. - Sensitization of the skin to the effects of the sun. - Marked fall in white blood cells which can develop in onset or recrudescence of fever, accompanied or not by signs of infection. - Abnormal fall in blood platelets, which can show up by bleeding from the nose or gums - Others effects are more common: - Drowsiness, impaired alertness, more so at the start of treatment. - Impaired memory or concentration, dizziness. - Motor incoordination, tremor. - Confusion, hallucinations. - Dry mouth, visual troubles, retention of urine, constipation, palpitations, low blood pressure. -More rarely: Signs of excitation (agitation, nervousness, insomnia) may occur. Do not hesitate to ask your Physician or Pharmacist for advice and to report any undesirable effect not mentioned in this leaflet.

Interactions:

In order to avoid possible interactions with other drugs, in particular sultopride or drugs containing alcohol, you should inform your Physician or Pharmacist about any other current treatment. This drug contains an antihistamine, oxomemazine, and guaifenesin (antiseptic for respiratory tract). Other drugs also contain these substances Do not take them together, in order to avoid exceeding the maximum suggested dose

Warnings:

Taking this drug requires MEDICAL ADVICE, - In the elderly: - predisposed to constipation, dizziness or drowsiness. - with prostate troubles. - In children with asthma or gastro-oesophageal reflux. - If you suffer from serious heart disease, or epilepsy. Pregnancy: this drug SHOULD GENERALLY NOT BE USED, unless otherwise advised by your Physician, during the first three months of pregnancy. If you discover that you are pregnant while you are taking this drug, immediately consult your Physician who can alone determine proper treatment in your condition. Abusive use of this drug at the end of pregnancy may have serious consequences on the newborn baby. You should therefore always ask your Physician for advice before taking this drug and never exceed the suggested dose and treatment duration. - Lactation: this drug is excreted in breast milk. Because of its marked sedative properties, it should be avoided by nursing mothers.

Form:

CAPSULE

Dosage and Administration

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Consultants Corner

Dr . Dirar Abboud

Dr . Dirar Abboud Hepatologist – Gastroenterologist

Samir Moussa M.D.

Samir Moussa M.D. ENT Specialist

Dr. Talal Sabouni

Dr. Talal Sabouni UROLOGY AND KIDNEY TRANSPLANT

Yaser Habrawi , F.R.C.S.Ed

Yaser Habrawi , F.R.C.S.Ed Consultant Ophthalmologist

Dr. Hani Najjar

Dr. Hani Najjar Pediatrics, Neurology

Dr. Samer Al-Jneidy

Dr. Samer Al-Jneidy Pediatrician

Dr. Tahsin Martini

Dr. Tahsin Martini Degree status: M.D. in Ophthalmology

Dr. Faisal Dibsi

Dr. Faisal Dibsi Specialist of Otolaryngology - Head and Neck Surgery
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