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Marijuana Users Protected Against Diabetes

Marijuana Users Protected Against Diabetes

(ePharmaNews) We are neither inviting, nor advertising for the use of this illegal drug, but a new study has pointed out that marijuana's users have decreased prevalence of diabetes mellitus.

Marijuana is considered the most widespread illegal drug in the world according to UN reports; it contains more than 400 chemical substances, that scientists are not aware of the complete evils of.
A team of researchers did the study by analyzing data from more than 10,000 people categorized according to the heaviness of their use of marijuana. They studied the incidence of diabetes among the participants, and the prevalence of other factors that can associate with diabetes per se; BMI, age, smoking history, alcohol, cholesterol and some inflammatory markers like CRP.
The results confirmed that diabetes was as twice as common in non-users compared to users, for reasons that scientists are not aware of.
Anyway, further analysis of the results revealed that CRP levels tend to be lower in marijuana users, which leaves a question mark whether this "anti-inflammatory-like" effect can have a protective role, especially that previous studies have linked CRP increased levels with diabetes.
"We postulate that the decreased prevalence of DM and marijuana use may be due to the anti-inflammatory properties of marijuana. The Cannabis sativa (marijuana) plant contains bioactive components termed cannabinoids (CBs). These CBs found in marijuana favorably modify inflammation probably through the inhibitory actions on prostaglandins" said Dr.Magda Shaheen, the lead author of the study, in an email to ePharmaNews. "Of note, the CRP assay used in [the study] was not a highly sensitive assay and is unlikely to pick up small changes in an inflammatory state in a single individual, however, it is still a robust measure of inflammation and is useful in population studies."
The study, which was published in BMJ, concludes that further researches are required to fully expose the relationship between the two, but whether these projects will lead to a possible "drug" for diabetes is a question that scientists are working on.

Prepared by: Mohammed Kanjo

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