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Stroke: Treatment at The Scene May Be the Solution

 Stroke: Treatment at The Scene May Be the Solution

(ePharmaNews) - According to the generally accepted ‘time is brain’ concept, which summarize the idea that the main problem in stroke treatment is timing, i.e. the time from the initial call for help to treatment decision, so researchers make a huge efforts to reduce that time and suggest that using a specialized ambulance or mobile stroke unit (MSU) may be a useful solution.

In a study published Online First in The Lancet Neurology, a German researchers tested a specialized ambulance or mobile stroke unit (MSU) to assess and treat patients who had a suspected stroke at the site of the emergency. They found that the MSUs halve the time from the initial call of help to treatment decision, which could increase the number of patients eligible for the life-saving treatment, clot busters.

Currently, the only treatment for 80% of stroke which is called acute ischemic stroke (in which blood flow to an area of the brain is blocked or reduced) is thrombolysis using the clot-buster drug alteplase (recombinant tissue plasminogen activator) within 4.5 hours of symptom onset. Patients must have computed tomography (CT) scans of the brain before treatment begins to confirm that a clot is the cause of the stroke, which makes the management a time race.

The results of this study, included 100 patients, showed that prehospital treatment with those MSUs that are equipped with CT-Scan substantially reduced the median time from the emergency call to therapy decision compared with hospital care (35 min vs. 76 min). The MSU also lowered the time from symptoms onset to therapy decision time to less than an hour for 57% of patients compared with just 4% in the hospital-care group.

“The MSU strategy offers a potential solution to the medical problem of the arrival of most stroke patients at the hospital too late for treatment…and substantially breaks, to our knowledge, all reported times or stroke management”, explains the lead author of the study.

However, in secondary analyses, no significant difference was recorded in the numbers of patients who received thrombolysis or in neurological outcome. The researchers responded that this study was designed to study the MSU and not the improvement in the medical outcomes, as the number of patients in the study was a little bit small, so further studies that may shed light on the usefulness of these MSUs in saving the lives of people with strokes compared with treating them in hospital.

اضغط هنا للقراءة باللغة العربية

Prepared by: Basel AlJunaidy
Translated by: Marcell Shehwaro

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