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One Botox Shot can Prevent MS Tremor

One Botox Shot can Prevent MS Tremor

(epharmanews) – Tremor or shaking in the arms of people with Multiple Sclerosis (MS) may be stopped by using botulinum toxin (or botox) which is used in cosmetic surgeries, according to a new research published the July 3, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

Researchers from the University of Melbourne, Australia, conducted a study to discover the most effective treatment for the tremors that MS patients suffer from, since these tremors are of the most exhausting symptoms. They gave 23 MS patients botulinum toxin type A injections or a saline placebo for three months. Scientists measured the tremor severity and their ability to write and draw before, during and after receiving the treatments. Video assessments were also taken every six weeks for six months.

The researchers found a significant improvement in tremor severity, writing and drawing after six weeks and after three months of botox treatment, compared to after placebo. Tremor severity was reduced from moderate to mild or two points on a 10-point scale.
Writing and drawing also improved by an average of one point on a 10-point scale.

“Our study suggests a new way to approach arm tremor related to MS where there are currently major treatment challenges and it also sets the framework for larger studies,” Said study author Anneke van der Walt, MD, consultant neurologist at The Royal Melbourne Hospital and research fellow with the University of Melbourne in Australia.

In 42 percent of the participants, muscle weakness improved after treatment with botolinum toxin, compared to only six percent after placebo. The weakness was generally mild and went away within two weeks.

This new study should offer hope for people with MS. “Treatments in use for tremor in MS are not sufficiently effective and new alternatives are needed,” said van der Walt.

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